SF1670

Catalog No. A13475

SF1670是选择性PTEN抑制剂（IC50 = 2 uM）。由于PTEN-mTOR通路对于控制皮质脊髓神经元的再生能力至关重要，因此PTEN缺失或其抑制剂可增强成年皮质脊髓神经元的再生能力。在临床相关的小鼠模型中，用SF1670进行预处理可增强粒细胞输注的功效。

Technical details

Catalog Num	A13475
M. Wt	307.4
Formula	C19H17NO3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	345630-40-2
Synonyms	SF 1670, SF-1670
SMILES	CC(C)(C)C(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C(=O)C2=O

Biological Activity

Targets

PTEN
2 μM

Solubility *

In vitro	DMSO	Warmed: 27 mg/mL (87.84 mM)
	Water	Insoluble
	Ethanol	Warmed: 1 mg/mL (3.25 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.53 mL	162.65 mL	325.31 mL
0.5 mM	6.51 mL	32.53 mL	65.06 mL
1 mM	3.25 mL	16.27 mL	32.53 mL
5 mM	0.65 mL	3.25 mL	6.51 mL

*The above data is based on the productmolecular weight 307.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.