Pamapimod (R-1503)

Catalog No. A13551

Pamapimod (R-1503)是一种新型p38丝裂原活化蛋白激酶抑制剂。

Technical details

Catalog Num	A13551
M. Wt	406.38
Formula	C19H20F2N4O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	449811-01-2
Synonyms	R 1503, R1503, R-1503, Ro 4402257, Ro4402257, Ro-4402257
SMILES	CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO

Biological Activity

Pamapimod (R-1503)是一种新型p38丝裂原活化蛋白激酶抑制剂。

Targets

p38α MAPK	p38β MAPK
0.014 μM	0.48 μM

Solubility *

In vitro	DMSO	70 mg/mL (172.25 mM)
	Water	Insoluble
	Ethanol	24 mg/mL (59.06 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.61 mL	123.04 mL	246.08 mL
0.5 mM	4.92 mL	24.61 mL	49.22 mL
1 mM	2.46 mL	12.3 mL	24.61 mL
5 mM	0.49 mL	2.46 mL	4.92 mL

*The above data is based on the productmolecular weight 406.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.