Parsaclisib
Catalog No. A13561
Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.
| Catalog Num | A13561 |
|---|---|
| M. Wt | 432.88 |
| Formula | C20H22ClFN6O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1426698-88-5 |
| Synonyms | INCB050465, INCB-050465, INCB 050465 |
| SMILES | CCOC1=C([C@@H](C2)CNC2=O)C(F)=C(Cl)C=C1[C@@H](N3C4=NC=NC(N)=C4C(C)=N3)C |
Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.1 mL | 115.51 mL | 231.01 mL |
| 0.5 mM | 4.62 mL | 23.1 mL | 46.2 mL |
| 1 mM | 2.31 mL | 11.55 mL | 23.1 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
*The above data is based on the productmolecular weight 432.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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