Alogliptin

Catalog No. A13571

Alogliptin是一种有效的DPP-4选择性抑制剂，IC50 <10 nM，与DPP-8和DPP-9相比具有超过10,000倍的选择性。

Technical details

Catalog Num	A13571
M. Wt	339.397
Formula	C18H21N5O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	850649-61-5
Synonyms	SYR-322, Axagliptin hydrate
SMILES	CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N

Biological Activity

Alogliptin是一种有效的DPP-4选择性抑制剂，IC50 <10 nM，与DPP-8和DPP-9相比具有超过10,000倍的选择性。

Targets

DPP-4
<10 nM

Solubility *

In vitro	DMSO	59 mg/mL (173.84 mM)
	Water	16 mg/mL (47.14 mM)
	Ethanol	59 mg/mL (173.84 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.46 mL	147.32 mL	294.64 mL
0.5 mM	5.89 mL	29.46 mL	58.93 mL
1 mM	2.95 mL	14.73 mL	29.46 mL
5 mM	0.59 mL	2.95 mL	5.89 mL

*The above data is based on the productmolecular weight 339.397. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.