YZ129
Catalog No. A13601
YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation.
Catalog Num | A13601 |
---|---|
M. Wt | 300.31 |
Formula | C19H12N2O2 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1643120-60-8 |
Synonyms | YZ 129, YZ-129 |
SMILES | O=C(C1=CC=CC=C1C(NC2=CC=C(C=NC=C3)C3=C2)=C4)C4=O |
YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 33.3 mL | 166.49 mL | 332.99 mL |
0.5 mM | 6.66 mL | 33.3 mL | 66.6 mL |
1 mM | 3.33 mL | 16.65 mL | 33.3 mL |
5 mM | 0.67 mL | 3.33 mL | 6.66 mL |
*The above data is based on the productmolecular weight 300.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.