Guanabenz acetate

Catalog No. A13635

Guanabenz acetate是a2A-AR肾上腺素能激动剂和IGRS（咪唑啉I2结合位点）选择性配体。

Technical details

Catalog Num	A13635
M. Wt	291.13
Formula	C10H12Cl2N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	23256-50-0
Synonyms
SMILES	CC(=O)O.C1=CC(=C(C(=C1)Cl)/C=N/N=C(N)N)Cl

Biological Activity

Guanabenz acetate是a2A-AR肾上腺素能激动剂和IGRS（咪唑啉I2结合位点）选择性配体。

Targets

α2a-adrenergic receptor	α2b-adrenergic receptor	α2c-adrenergic receptor
8.25(pEC50)	7.01(pEC50)	<5(pEC50)

Solubility *

In vitro (25°C)	DMSO	56 mg/mL (192.35 mM)
	Water	Insoluble
	Ethanol	5 mg/mL (17.17 mM)
In vivo	4% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	34.35 mL	171.74 mL	343.49 mL
0.5 mM	6.87 mL	34.35 mL	68.7 mL
1 mM	3.43 mL	17.17 mL	34.35 mL
5 mM	0.69 mL	3.43 mL	6.87 mL

*The above data is based on the productmolecular weight 291.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.