20-Hydroxyecdysone

Catalog No. A13916

20-Hydroxyecdysone是节肢动物体内产生的蜕皮甾类激素，可诱导与蜕皮和变态完成相关的发育变化。

Product Citations

Chunyan Fang, .et al. The Hox gene Antennapedia is essential for wing development in insects, Development, 2022, Jan 15;149(2):dev199841 PMID: 35088829
Miwako Toyofuku, .et al. The plant-derived triterpenoid, cucurbitacin B, but not cucurbitacin E, inhibits the developmental transition associated with ecdysone biosynthesis in Drosophila melanogaster, J Insect Physiol, 2021, Oct;134:104294 PMID: 34389412

Technical details

Catalog Num	A13916
M. Wt	480.6
Formula	C27H44O7
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	5289-74-7
Synonyms	β-Ecdysone, Ecdysterone
SMILES	C[C@]12CC[C@H]3C(=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)[C@@]1(CC[C@@H]2[C@](C)([C@@H](CCC(C)(C)O)O)O)O

Biological Activity

20-Hydroxyecdysone是节肢动物体内产生的蜕皮甾类激素，可诱导与蜕皮和变态完成相关的发育变化。

Solubility *

In vitro (25°C)	DMSO	86 mg/mL (178.92 mM)
	Water	Insoluble
	Ethanol	86 mg/mL (178.92 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.81 mL	104.04 mL	208.07 mL
0.5 mM	4.16 mL	20.81 mL	41.61 mL
1 mM	2.08 mL	10.4 mL	20.81 mL
5 mM	0.42 mL	2.08 mL	4.16 mL

*The above data is based on the productmolecular weight 480.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.