WK23
Catalog No. A14051
WK23是基于四个芳香族基团的抑制剂,能够有效填充MDM2/MDMX的结合口袋,其对MDM2/MDMX的中位抑制浓度(IC50)值分别为1.17和36 uM。
Catalog Num | A14051 |
---|---|
M. Wt | 462.33 |
Formula | C25H17Cl2N3O2 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | |
Synonyms | WK-23, WK 23 |
SMILES |
WK23是基于四个芳香族基团的抑制剂,能够有效填充MDM2/MDMX的结合口袋,其对MDM2/MDMX的中位抑制浓度(IC50)值分别为1.17和36 uM。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.63 mL | 108.15 mL | 216.3 mL |
0.5 mM | 4.33 mL | 21.63 mL | 43.26 mL |
1 mM | 2.16 mL | 10.81 mL | 21.63 mL |
5 mM | 0.43 mL | 2.16 mL | 4.33 mL |
*The above data is based on the productmolecular weight 462.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.