JSH 23

Catalog No. A14142

JSH 23是NF-kB的抑制剂，可阻止其转运入细胞核（IC50 = 7.1 uM）。

Product Citations

Yu N, .et al. Low-Dose Radiation Promotes Dendritic Cell Migration and IL-12 Production via the ATM/NF-KappaB Pathway, Radiat Res, 2018, Apr;189(4):409-417 PMID: 29420126

Technical details

Catalog Num	A14142
M. Wt	240.3
Formula	C16H20N2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	749886-87-1
Synonyms	JSH-23,JSH23, NF??B Activation Inhibitor II
SMILES	CC1=CC(=C(C=C1)NCCCC2=CC=CC=C2)N

Biological Activity

JSH 23是NF-kB的抑制剂，可阻止其转运入细胞核（IC50 = 7.1 uM）。

Solubility *

In vitro	DMSO	41 mg/mL (170.59 mM)
	Water	Insoluble
	Ethanol	17 mg/mL (70.73 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	41.61 mL	208.07 mL	416.15 mL
0.5 mM	8.32 mL	41.61 mL	83.23 mL
1 mM	4.16 mL	20.81 mL	41.61 mL
5 mM	0.83 mL	4.16 mL	8.32 mL

*The above data is based on the productmolecular weight 240.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.