SB265610
Catalog No. A14195
SB265610是CXCR2 (Kd = 2.51 nM)的非肽变构反向激动剂，通过与不同于激动剂结合位点的区域结合来防止受体活化。它不与相关CXCR1受体结合。在体外和高氧诱导肺损伤的大鼠模型中，它已被证明能防止中性粒细胞趋化性。
| Catalog Num | A14195 |
|---|---|
| M. Wt | 357.16 |
| Formula | C14H9BrN6O |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 211096-49-0 |
| Synonyms | SB 265610,SB-265610 |
| SMILES | C1=CC=C(C(=C1)NC(=O)NC2=CC=C(C3=NNN=C23)C#N)Br |
SB265610是CXCR2 (Kd = 2.51 nM)的非肽变构反向激动剂，通过与不同于激动剂结合位点的区域结合来防止受体活化。它不与相关CXCR1受体结合。在体外和高氧诱导肺损伤的大鼠模型中，它已被证明能防止中性粒细胞趋化性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28 mL | 139.99 mL | 279.99 mL |
| 0.5 mM | 5.6 mL | 28 mL | 56 mL |
| 1 mM | 2.8 mL | 14 mL | 28 mL |
| 5 mM | 0.56 mL | 2.8 mL | 5.6 mL |
*The above data is based on the productmolecular weight 357.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
ADOOQ 产品质量保证
We promise all products to perform as described.