Metoclopramide HCl

Catalog No. A14247

Metoclopramide HCl是一种选择性的多巴胺D2受体拮抗剂。

Product Citations

Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Technical details

Catalog Num	A14247
M. Wt	336.26
Formula	C14H23Cl2N3O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	7232-21-5
Synonyms	0
SMILES	CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl.Cl

Biological Activity

Metoclopramide HCl是一种选择性的多巴胺D2受体拮抗剂。

Targets

D2 receptor

Solubility *

In vitro	DMSO	Warmed: 59 mg/mL (175.46 mM)
	Water	59 mg/mL (175.46 mM)
	Ethanol	59 mg/mL (175.46 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.74 mL	148.69 mL	297.39 mL
0.5 mM	5.95 mL	29.74 mL	59.48 mL
1 mM	2.97 mL	14.87 mL	29.74 mL
5 mM	0.59 mL	2.97 mL	5.95 mL

*The above data is based on the productmolecular weight 336.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.