UNC2881

Catalog No. A14276

UNC2881是特异的Mer酪氨酸激酶抑制剂。

Technical details

Catalog Num	A14276
M. Wt	463.58
Formula	C25H33N7O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1493764-08-1
Synonyms	UNC 2881, UNC-2881
SMILES	CCCCNC1=NC=C(C(=N1)NC2CCC(CC2)O)C(=O)NCC3=CC=C(C=C3)N4C=CN=C4

Biological Activity

UNC2881是特异的Mer酪氨酸激酶抑制剂。

Targets

Mer	Tyro3	Axl
4.3 nM	250 nM	360 nM

Solubility *

In vitro	DMSO	80 mg/mL (172.57 mM)
	Water	Insoluble
	Ethanol	Warmed: 4 mg/mL (8.62 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.57 mL	107.86 mL	215.71 mL
0.5 mM	4.31 mL	21.57 mL	43.14 mL
1 mM	2.16 mL	10.79 mL	21.57 mL
5 mM	0.43 mL	2.16 mL	4.31 mL

*The above data is based on the productmolecular weight 463.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.