BMH-21

Catalog No. A14335

BMH-21是有效的小分子DNA嵌入剂。BMH-21结合核糖体DNA并抑制RNA聚合酶I转录。

Product Citations

Masahiko Okuda, .et al. Three human RNA polymerases interact with TFIIH via a common RPB6 subunit, Nucleic Acids Res, 2021, Jul 16 PMID: 34268577

Technical details

Catalog Num	A14335
M. Wt	362.43
Formula	C21H22N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	896705-16-1
Synonyms	BMH21, BMH 21
SMILES	CN(C)CCNC(=O)C1=CC=CN2C1=NC3=CC4=CC=CC=C4C=C3C2=O

Biological Activity

BMH-21是有效的小分子DNA嵌入剂。BMH-21结合核糖体DNA并抑制RNA聚合酶I转录。

Targets

RNA polymerase I

Solubility *

In vitro	DMSO	Warmed: 4 mg/mL (11.1 mM)
	Water	Insoluble
	Ethanol	Warmed: 2 mg/mL (5.54 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.59 mL	137.96 mL	275.92 mL
0.5 mM	5.52 mL	27.59 mL	55.18 mL
1 mM	2.76 mL	13.8 mL	27.59 mL
5 mM	0.55 mL	2.76 mL	5.52 mL

*The above data is based on the productmolecular weight 362.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.