LJI308

Catalog No. A14373

LJI308是一种新型的有效的全RSK抑制剂，对于RSK1，RSK2和RSK3的IC50分别为6 nM，4 nM和13 nM。

Technical details

Catalog Num	A14373
M. Wt	368.38
Formula	C21H18F2N2O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1627709-94-7
Synonyms	LJI 308, LJI-30
SMILES	OC1=C(F)C=C(C2=C(C3=CC=C(N4CCOCC4)C=C3)C=CN=C2)C=C1F

Biological Activity

LJI308是一种新型的有效的全RSK抑制剂，对于RSK1，RSK2和RSK3的IC50分别为6 nM，4 nM和13 nM。

Targets

RSK2	RSK1	RSK3
4 nM	6 nM	13 nM

Solubility *

In vitro	DMSO	Warmed: 66 mg/mL (179.16 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.15 mL	135.73 mL	271.46 mL
0.5 mM	5.43 mL	27.15 mL	54.29 mL
1 mM	2.71 mL	13.57 mL	27.15 mL
5 mM	0.54 mL	2.71 mL	5.43 mL

*The above data is based on the productmolecular weight 368.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.