CYT387 sulfate salt

Catalog No. A15056

CYT387 sulfate salt是JAK1/JAK2的ATP竞争性抑制剂,IC50为11 nM/18 nM,是JAK3的约10倍选择性。
Catalog Num A15056
M. Wt 610.62
Formula C23H26N6O10S2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1056636-06-6
Synonyms CYT-387 sulfate, CYT 387 sulfate, momelotinib sulfate
SMILES C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N.OS(=O)(=O)O.OS(=O)(=O)O
CYT387 sulfate salt是JAK1/JAK2的ATP竞争性抑制剂,IC50为11 nM/18 nM,是JAK3的约10倍选择性。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.38 mL 81.88 mL 163.77 mL
0.5 mM 3.28 mL 16.38 mL 32.75 mL
1 mM 1.64 mL 8.19 mL 16.38 mL
5 mM 0.33 mL 1.64 mL 3.28 mL

*The above data is based on the productmolecular weight 610.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.