Regorafenib monohydrate
Catalog No. A15218
Regorafenib monohydrate是VEGFR1/VEGFR2/VEGFR3/PDGFRβ/Kit/RET和Raf-1的多靶点抑制剂，IC50分别为13 nM/4.2 nM/46 nM/22 nM/7 nM/1.5 nM和2.5 nM。
| Catalog Num | A15218 |
|---|---|
| M. Wt | 500.83 |
| Formula | C21H17ClF4N4O4 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1019206-88-2 |
| Synonyms | BAY 73-4506 monohydrate |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O |
Regorafenib monohydrate是VEGFR1/VEGFR2/VEGFR3/PDGFRβ/Kit/RET和Raf-1的多靶点抑制剂，IC50分别为13 nM/4.2 nM/46 nM/22 nM/7 nM/1.5 nM和2.5 nM。
| In vitro | DMSO | 93 mg/mL (185.68 mM) | |
| Water | |||
| Ethanol | <1 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.97 mL | 99.83 mL | 199.67 mL |
| 0.5 mM | 3.99 mL | 19.97 mL | 39.93 mL |
| 1 mM | 2 mL | 9.98 mL | 19.97 mL |
| 5 mM | 0.4 mL | 2 mL | 3.99 mL |
*The above data is based on the productmolecular weight 500.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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