Retigabine dihydrochloride

Catalog No. A15222

Retigabine dihydrochloride是具有抗惊厥活性的Kv7.2-7.5（KCNQ2-5）神经元钾通道开放剂。

Technical details

Catalog Num	A15222
M. Wt	376.25
Formula	C16H20Cl2FN3O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	150812-13-8
Synonyms	D 20443 dihydrochloride, D-20443 dihydrochloride, D20443 dihydrochloride
SMILES	CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N.Cl.Cl

Biological Activity

Retigabine dihydrochloride是具有抗惊厥活性的Kv7.2-7.5（KCNQ2-5）神经元钾通道开放剂。

Solubility *

In vitro	DMSO	65 mg/mL (172.75 mM)
	Water	65 mg/mL (172.75 mM)
	Ethanol	22 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.58 mL	132.89 mL	265.78 mL
0.5 mM	5.32 mL	26.58 mL	53.16 mL
1 mM	2.66 mL	13.29 mL	26.58 mL
5 mM	0.53 mL	2.66 mL	5.32 mL

*The above data is based on the productmolecular weight 376.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Retigabine dihydrochloride

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions