KC7F2

Catalog No. A15359

KC7F2是HIF-1α蛋白翻译的抑制剂，但不是转录的抑制剂，可抑制蛋白质合成的两个关键调节子，即真核翻译起始因子4E结合蛋白1（4EBP1）和p70 S6激酶（S6K）的磷酸化。

Technical details

Catalog Num	A15359
M. Wt	570.38
Formula	C16H16Cl4N2O4S4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	927822-86-4
Synonyms
SMILES	C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl

Biological Activity

Targets

HIF-1α
20 μM

Solubility *

In vitro	DMSO	94 mg/mL (164.8 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.53 mL	87.66 mL	175.32 mL
0.5 mM	3.51 mL	17.53 mL	35.06 mL
1 mM	1.75 mL	8.77 mL	17.53 mL
5 mM	0.35 mL	1.75 mL	3.51 mL

*The above data is based on the productmolecular weight 570.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.