Genz-123346 free base

Catalog No. A15442

Genz-123346 free base是GL1合酶的抑制剂,可阻止神经酰胺向GL1的转化。抑制GM1的IC50为14 nM。
Catalog Num A15442
M. Wt 418.57
Formula C24H38N2O4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 491833-30-8
Synonyms Genz123346
SMILES CCCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O
Genz-123346 free base是GL1合酶的抑制剂,可阻止神经酰胺向GL1的转化。抑制GM1的IC50为14 nM。
In vitro DMSO 77 mg/mL (183.96 mM)
Water Insoluble
Ethanol 77 mg/mL (183.96 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.89 mL 119.45 mL 238.91 mL
0.5 mM 4.78 mL 23.89 mL 47.78 mL
1 mM 2.39 mL 11.95 mL 23.89 mL
5 mM 0.48 mL 2.39 mL 4.78 mL

*The above data is based on the productmolecular weight 418.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.