AV412

Catalog No. A15460

AV-412 (MP412)是一种EGFR抑制剂，对EGFR，EGFRL858R，EGFRT790M，EGFRL858R/T790M和ErbB2的IC50分别为0.75、0.5、0.79、2.3、19 nM。

Technical details

Catalog Num	A15460
M. Wt	507.02
Formula	C27H28ClFN6O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	451492-95-8
Synonyms	av 412, av-412, MP 412, MP-412
SMILES	O=S(C1=CC=C(C)C=C1)(O)=O.C=CC(NC2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2C#CC(N5CCN(C)CC5)(C)C)=O.O=S(C6=CC=C(C)C=C6)(O)=O

Biological Activity

AV-412 (MP412)是一种EGFR抑制剂，对EGFR，EGFRL858R，EGFRT790M，EGFRL858R/T790M和ErbB2的IC50分别为0.75、0.5、0.79、2.3、19 nM。

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.72 mL	98.62 mL	197.23 mL
0.5 mM	3.94 mL	19.72 mL	39.45 mL
1 mM	1.97 mL	9.86 mL	19.72 mL
5 mM	0.39 mL	1.97 mL	3.94 mL

*The above data is based on the productmolecular weight 507.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

AV412

Technical details

Biological Activity

Preparing Stock Solutions