CZC54252 hydrochloride

Catalog No. A15510

CZC54252 hydrochloride是一种有效的LRRK2抑制剂,野生型和G2019S LRRK2的IC50分别为1.28 nM和1.85 nM。
Catalog Num A15510
M. Wt 541.45
Formula C22H25ClN6O4S.HCl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1191911-27-9
Synonyms CZC-54252 hydrochloride, CZC 54252 hydrochloride
SMILES COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl.Cl
CZC54252 hydrochloride是一种有效的LRRK2抑制剂,野生型和G2019S LRRK2的IC50分别为1.28 nM和1.85 nM。
In vitro DMSO 85 mg/mL (168.32 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.47 mL 92.34 mL 184.69 mL
0.5 mM 3.69 mL 18.47 mL 36.94 mL
1 mM 1.85 mL 9.23 mL 18.47 mL
5 mM 0.37 mL 1.85 mL 3.69 mL

*The above data is based on the productmolecular weight 541.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.