AI-10-49

Catalog No. A15521

AI-10-49是一种蛋白质-蛋白质相互作用抑制剂,可选择性结合CBFβ-SMMHC并以0.26 uM的FRET IC50破坏其与RUNX1的结合。
Catalog Num A15521
M. Wt 660.52
Formula C30H22F6N6O5
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1256094-72-0
Synonyms
SMILES C1=CC2=C(C=C1OC(F)(F)F)NC(=N2)C3=NC=C(C=C3)OCCOCCOC4=CN=C(C=C4)C5=NC6=C(N5)C=C(C=C6)OC(F)(F)F
AI-10-49是一种蛋白质-蛋白质相互作用抑制剂,可选择性结合CBFβ-SMMHC并以0.26 uM的FRET IC50破坏其与RUNX1的结合。
Targets
CBFβ-SMMHC
260 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.14 mL 75.7 mL 151.4 mL
0.5 mM 3.03 mL 15.14 mL 30.28 mL
1 mM 1.51 mL 7.57 mL 15.14 mL
5 mM 0.3 mL 1.51 mL 3.03 mL

*The above data is based on the productmolecular weight 660.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.