TH588

Catalog No. A15537

TH588是一流的nudix水解酶家族抑制剂，可有效和选择性地参与并抑制细胞中的MTH1（IC50 = 5 nM）。

Technical details

Catalog Num	A15537
M. Wt	295.17
Formula	C13H12Cl2N4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1609960-31-7
Synonyms	TH-588, TH 588
SMILES	C1CC1NC2=NC(=NC(=C2)C3=C(C(=CC=C3)Cl)Cl)N

Biological Activity

TH588是一流的nudix水解酶家族抑制剂，可有效和选择性地参与并抑制细胞中的MTH1（IC50 = 5 nM）。

Targets

MTH1 (NUDT1)
5 nM

Solubility *

In vitro	DMSO	Warmed: 19 mg/mL (64.36 mM)
	Water	Insoluble
	Ethanol	Warmed: 1 mg/mL (3.38 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.88 mL	169.39 mL	338.79 mL
0.5 mM	6.78 mL	33.88 mL	67.76 mL
1 mM	3.39 mL	16.94 mL	33.88 mL
5 mM	0.68 mL	3.39 mL	6.78 mL

*The above data is based on the productmolecular weight 295.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.