NVP-TNKS656

Catalog No. A15786

NVP-TNKS656是一种高效，选择性和活性的TNKS2抑制剂，IC50为6 nM。对PARP1和PARP2的选择性> 300倍。

Technical details

Catalog Num	A15786
M. Wt	494.58
Formula	C27H34N4O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1419949-20-4
Synonyms	TNKS656, TNKS-656
SMILES	COC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5

Biological Activity

NVP-TNKS656是一种高效，选择性和活性的TNKS2抑制剂，IC50为6 nM。对PARP1和PARP2的选择性> 300倍。

Targets

Solubility *

In vitro	DMSO	89 mg/mL (179.95 mM)
	Water	Insoluble
	Ethanol	Warmed: 9 mg/mL (18.19 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.22 mL	101.1 mL	202.19 mL
0.5 mM	4.04 mL	20.22 mL	40.44 mL
1 mM	2.02 mL	10.11 mL	20.22 mL
5 mM	0.4 mL	2.02 mL	4.04 mL

*The above data is based on the productmolecular weight 494.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.