CB5083
Catalog No. A15827
CB-5083是新型的,一流的,有效的生物可利用的p97抑制剂,可破坏细胞蛋白稳态并在固体和血液学模型中显示出抗肿瘤活性。
Catalog Num | A15827 |
---|---|
M. Wt | 413.4 |
Formula | C24H23N5O2 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1542705-92-9 |
Synonyms | CB-5083, CB 5083 |
SMILES | CC1=CC2=C(C=CC=C2N1C3=NC4=C(COCC4)C(=N3)NCC5=CC=CC=C5)C(=O)N |
CB-5083是新型的,一流的,有效的生物可利用的p97抑制剂,可破坏细胞蛋白稳态并在固体和血液学模型中显示出抗肿瘤活性。
Targets
p97 AAA ATPase | ||||
11 nM |
In vitro (25°C) | DMSO | 74 mg/mL (178.97 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 12 mg/mL (29.02 mM) | ||
In vivo | 0.5% CMC Na+5% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.19 mL | 120.95 mL | 241.9 mL |
0.5 mM | 4.84 mL | 24.19 mL | 48.38 mL |
1 mM | 2.42 mL | 12.09 mL | 24.19 mL |
5 mM | 0.48 mL | 2.42 mL | 4.84 mL |
*The above data is based on the productmolecular weight 413.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.