UNC-2025

Catalog No. A15904

UNC-2025是一种有效的且可生物利用的双重MER/FLT3抑制剂，IC50分别为0.74 nM和0.8 nM，选择性是Axl和Tyro3的20倍。

Technical details

Catalog Num	A15904
M. Wt	513.12
Formula	C28H41ClN6O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1429881-91-3
Synonyms	UNC 2025, UNC-2025
SMILES	CN1CCN(CC2=CC=C(C3=CN([C@@H]4CC[C@@H](O)CC4)C5=NC(NCCCC)=NC=C35)C=C2)CC1

Biological Activity

UNC-2025是一种有效的且可生物利用的双重MER/FLT3抑制剂，IC50分别为0.74 nM和0.8 nM，选择性是Axl和Tyro3的20倍。

Solubility *

In vitro	DMSO	88 mg/mL (184.62 mM)
	Water	Insoluble
	Ethanol	53 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.49 mL	97.44 mL	194.89 mL
0.5 mM	3.9 mL	19.49 mL	38.98 mL
1 mM	1.95 mL	9.74 mL	19.49 mL
5 mM	0.39 mL	1.95 mL	3.9 mL

*The above data is based on the productmolecular weight 513.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

UNC-2025

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions