VX-787 (Pimodivir)
Catalog No. A15993
VX-787 (Pimodivir)是一种新型的流感病毒复制抑制剂，可阻断流感病毒聚合酶复合物的PB2帽捕获功能。
- Jiri Gregor, .et al. Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase, Molecules, 2021, Feb; 26(4): 1007 PMID: 33673017
| Catalog Num | A15993 |
|---|---|
| M. Wt | 399.4 |
| Formula | C20H19F2N5O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1629869-44-8 |
| Synonyms | VX787, JNJ-872, JNJ 872, JNJ872, VRT-0928787 |
| SMILES | O=C([C@H]1C(CC2)CCC2[C@@H]1NC3=NC(C4=CNC5=NC=C(F)C=C54)=NC=C3F)O |
VX-787 (Pimodivir)是一种新型的流感病毒复制抑制剂，可阻断流感病毒聚合酶复合物的PB2帽捕获功能。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.04 mL | 125.19 mL | 250.38 mL |
| 0.5 mM | 5.01 mL | 25.04 mL | 50.08 mL |
| 1 mM | 2.5 mL | 12.52 mL | 25.04 mL |
| 5 mM | 0.5 mL | 2.5 mL | 5.01 mL |
*The above data is based on the productmolecular weight 399.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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