GSK744 (S/GSK1265744)

Catalog No. A16014

GSK744 (S/GSK1265744)是一种有效的HIV整合酶抑制剂，可作为口服导入片剂和长效注射剂，用于治疗和预防HIV感染。

Technical details

Catalog Num	A16014
M. Wt	405.35
Formula	C19H17F2N3O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1051375-10-0
Synonyms	Cabotegravir
SMILES	FC1=CC(F)=CC=C1CNC(C2=CN(C3=C(C2=O)O)C[C@H]4OC[C@H](C)N4C3=O)=O

Biological Activity

GSK744 (S/GSK1265744)是一种有效的HIV整合酶抑制剂，可作为口服导入片剂和长效注射剂，用于治疗和预防HIV感染。

Targets

HIV integrase

Solubility *

In vitro	DMSO	Warmed: 33 mg/mL (81.41 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.67 mL	123.35 mL	246.7 mL
0.5 mM	4.93 mL	24.67 mL	49.34 mL
1 mM	2.47 mL	12.34 mL	24.67 mL
5 mM	0.49 mL	2.47 mL	4.93 mL

*The above data is based on the productmolecular weight 405.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.