TRx0237 (LMTX) mesylate

Catalog No. A16124

TRx0237 (LMTX) mesylate是第二代tau蛋白聚集抑制剂，可用于治疗阿尔茨海默氏病（AD）和额颞痴呆。

Technical details

Catalog Num	A16124
M. Wt	477.62
Formula	C16H19N3S.2CH4O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1236208-20-0
Synonyms	Leucomethylene blue Mesylate
SMILES	CN(C)C1=CC2=C(C=C1)NC3=C(S2)C=C(C=C3)N(C)C.CS(=O)(=O)O.CS(=O)(=O)O

Biological Activity

TRx0237 (LMTX) mesylate是第二代tau蛋白聚集抑制剂，可用于治疗阿尔茨海默氏病（AD）和额颞痴呆。

Targets

tau protein aggregation

Solubility *

In vitro	DMSO	90 mg/mL (188.43 mM)
	Water	90 mg/mL (188.43 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.94 mL	104.69 mL	209.37 mL
0.5 mM	4.19 mL	20.94 mL	41.87 mL
1 mM	2.09 mL	10.47 mL	20.94 mL
5 mM	0.42 mL	2.09 mL	4.19 mL

*The above data is based on the productmolecular weight 477.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.