BI-9564

Catalog No. A16196

BI-9564是BRD9和BRD7溴结构域的有效和选择性抑制剂（Kds分别为14.1和239 nM；IC50分别为75 nM和3.4 uM）。

Technical details

Catalog Num	A16196
M. Wt	353.41
Formula	C20H23N3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1883429-22-8
Synonyms	BI 9564, BI9564
SMILES	O=C1N(C)C=C(C2=CC(OC)=C(CN(C)C)C=C2OC)C3=CC=NC=C13

Biological Activity

BI-9564是BRD9和BRD7溴结构域的有效和选择性抑制剂（Kds分别为14.1和239 nM；IC50分别为75 nM和3.4 uM）。

Targets

BRD9	BRD7	CECR2
5.9 nM(Kd)	73 nM(Kd)	77 nM(Kd)

Solubility *

In vitro	DMSO	3 mg/mL (8.48 mM)
	Water	Insoluble
	Ethanol	15 mg/mL (42.44 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.3 mL	141.48 mL	282.96 mL
0.5 mM	5.66 mL	28.3 mL	56.59 mL
1 mM	2.83 mL	14.15 mL	28.3 mL
5 mM	0.57 mL	2.83 mL	5.66 mL

*The above data is based on the productmolecular weight 353.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.