H3B-6527

Catalog No. A16252

H3B-6527是一种高度选择性的FGFR4抑制剂,在FGF19扩增的细胞系和小鼠中具有强大的抗肿瘤活性。
Catalog Num A16252
M. Wt 629.54
Formula C29H34Cl2N8O4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1702259-66-2
Synonyms H3B6527, H3B 6527
SMILES C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O
H3B-6527是一种高度选择性的FGFR4抑制剂,在FGF19扩增的细胞系和小鼠中具有强大的抗肿瘤活性。
In vitro DMSO 45 mg/mL (71.48 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.88 mL 79.42 mL 158.85 mL
0.5 mM 3.18 mL 15.88 mL 31.77 mL
1 mM 1.59 mL 7.94 mL 15.88 mL
5 mM 0.32 mL 1.59 mL 3.18 mL

*The above data is based on the productmolecular weight 629.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.