YL-0919

Catalog No. A16337

YL0919,具有5-HT1A受体激动剂和选择性5-羟色胺再摄取抑制剂双重活性的新型抗抑郁候选药物,YL-0919抑制5-HT被大鼠大脑皮层突触小体和人重组细胞摄取的IC50值为1.78±0.34 nM和1.93±0.18 nM。
Catalog Num A16337
M. Wt 334.84
Formula C18H23N2O2Cl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1339058-04-6
Synonyms YL-0919, YL 0919
SMILES O=C1C=CC=CN1CC2(O)CCN(CC3=CC=CC=C3)CC2.[H]Cl
YL0919,具有5-HT1A受体激动剂和选择性5-羟色胺再摄取抑制剂双重活性的新型抗抑郁候选药物,YL-0919抑制5-HT被大鼠大脑皮层突触小体和人重组细胞摄取的IC50值为1.78±0.34 nM和1.93±0.18 nM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.87 mL 149.33 mL 298.65 mL
0.5 mM 5.97 mL 29.87 mL 59.73 mL
1 mM 2.99 mL 14.93 mL 29.87 mL
5 mM 0.6 mL 2.99 mL 5.97 mL

*The above data is based on the productmolecular weight 334.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.