ML348
Catalog No. A16338
ML348是一种选择性和可逆的溶血磷脂酶1（LYPLA1）抑制剂（IC50 = 210 nM），与LYPLA2相比，对LYPLA1的选择性高14倍，对大约30种其他丝氨酸水解酶也具有选择性。
| Catalog Num | A16338 |
|---|---|
| M. Wt | 415.79 |
| Formula | C18H17ClF3N3O3 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 899713-86-1 |
| Synonyms | ML-348, ML 348 |
| SMILES | ClC1=C(NC(CN2CCN(C(C3=CC=CO3)=O)CC2)=O)C=C(C(F)(F)F)C=C1 |
ML348是一种选择性和可逆的溶血磷脂酶1（LYPLA1）抑制剂（IC50 = 210 nM），与LYPLA2相比，对LYPLA1的选择性高14倍，对大约30种其他丝氨酸水解酶也具有选择性。
| In vitro | DMSO | 77 mg/mL (185.19 mM) | |
| Water | Insoluble | ||
| Ethanol | 9 mg/mL (21.65 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.05 mL | 120.25 mL | 240.51 mL |
| 0.5 mM | 4.81 mL | 24.05 mL | 48.1 mL |
| 1 mM | 2.41 mL | 12.03 mL | 24.05 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.81 mL |
*The above data is based on the productmolecular weight 415.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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