Ambroxol HCl
Catalog No. A16398
Ambroxol HCl是神经元Na+通道的有效抑制剂，可抑制TTX耐受的Na+电流，IC50为35.2 uM，对于补品和相阻滞的IC50为22.5 μM，抑制TTX敏感的Na+电流，IC50为100 μM。第三阶段。
- Giovanni Bocci, .et al. Virtual and In Vitro Antiviral Screening Revive Therapeutic Drugs for COVID-19, ACS Pharmacol Transl Sci, 2020, Oct 14
| Catalog Num | A16398 |
|---|---|
| M. Wt | 414.56 |
| Formula | C13H18Br2N2O.HCl |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 23828-92-4 |
| Synonyms | |
| SMILES | C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl |
Ambroxol HCl是神经元Na+通道的有效抑制剂，可抑制TTX耐受的Na+电流，IC50为35.2 uM，对于补品和相阻滞的IC50为22.5 μM，抑制TTX敏感的Na+电流，IC50为100 μM。第三阶段。
| In vitro | DMSO | Warmed: 4 mg/mL (9.64 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.12 mL | 120.61 mL | 241.22 mL |
| 0.5 mM | 4.82 mL | 24.12 mL | 48.24 mL |
| 1 mM | 2.41 mL | 12.06 mL | 24.12 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.82 mL |
*The above data is based on the productmolecular weight 414.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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