ex229 (compound 991)

Catalog No. A16795

ex229 (compound 991)是一种有效的AMPK活化剂，在活化AMPK方面比A769662的效力高5-10倍。

Product Citations

CN Koyani, .et al. Empagliflozin Protects Heart From Inflammation and Energy Depletion via AMPK Activation, Pharmacol Res, 2020, May 17;158:104870 PMID: 32434052

Technical details

Catalog Num	A16795
M. Wt	431.87
Formula	C24H1ClN3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1219739-36-2
Synonyms	ex-229, ex 229
SMILES	O=C1C2=C(C(C)C)NN(C3=C(Cl)C=CC=C3Cl)C2=NC(CC4=CC=C(OCCO)C=C4)=N1

Biological Activity

ex229 (compound 991)是一种有效的AMPK活化剂，在活化AMPK方面比A769662的效力高5-10倍。

Solubility *

In vitro	DMSO	11 mg/mL (25.47 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.16 mL	115.78 mL	231.55 mL
0.5 mM	4.63 mL	23.16 mL	46.31 mL
1 mM	2.32 mL	11.58 mL	23.16 mL
5 mM	0.46 mL	2.32 mL	4.63 mL

*The above data is based on the productmolecular weight 431.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.