leniolisib (CDZ 173)

Catalog No. A16796

Leniolisib (CDZ 173)是一种有效的、选择性的PI3Kδ抑制剂，对PI3Kα、PI3Kβ、PI3Kγ和PI3Kδ的生化IC50值分别为0.244、0.424、2.23和0.011 uM。

Technical details

Catalog Num	A16796
M. Wt	450.46
Formula	C21H25F3N6O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1354690-24-6
Synonyms	Leniolisib; CDZ-173; CDZ 173; CDZ173; Leniosilib
SMILES	FC(C1=C(OC)N=CC(N(CCC2=NC=N3)CC2=C3N[C@@H]4CN(C(CC)=O)CC4)=C1)(F)F

Biological Activity

Leniolisib (CDZ 173)是一种有效的、选择性的PI3Kδ抑制剂，对PI3Kα、PI3Kβ、PI3Kγ和PI3Kδ的生化IC50值分别为0.244、0.424、2.23和0.011 uM。

Solubility *

In vitro	DMSO	81 mg/mL (179.81 mM)
	Water	Insoluble
	Ethanol	12 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.2 mL	111 mL	222 mL
0.5 mM	4.44 mL	22.2 mL	44.4 mL
1 mM	2.22 mL	11.1 mL	22.2 mL
5 mM	0.44 mL	2.22 mL	4.44 mL

*The above data is based on the productmolecular weight 450.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

leniolisib (CDZ 173)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions