Seletalisib (UCB-5857)

Catalog No. A16797

Seletalisib (UCB-5857)是一种新型的PI3Kδ小分子抑制剂，其IC50值为12 nM，相对于其他I类PI3K亚型（介于24-303倍之间），对PI3Kδ具有显著的选择性。

Technical details

Catalog Num	A16797
M. Wt	482.85
Formula	C23H14ClF3N6O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1362850-20-1
Synonyms	UCB-5857; UCB 5857; UCB5857; Seletalisib
SMILES	FC(F)(F)[C@@H](C1=CC2=CC=CC(Cl)=C2N=C1C3=CC=C[N+]([O-])=C3)NC4=C5C(C=CC=N5)=NC=N4

Biological Activity

Seletalisib (UCB-5857)是一种新型的PI3Kδ小分子抑制剂，其IC50值为12 nM，相对于其他I类PI3K亚型（介于24-303倍之间），对PI3Kδ具有显著的选择性。

Solubility *

In vitro	DMSO	89 mg/mL (184.32 mM)
	Water	Insoluble
	Ethanol	89 mg/mL (184.32 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.71 mL	103.55 mL	207.1 mL
0.5 mM	4.14 mL	20.71 mL	41.42 mL
1 mM	2.07 mL	10.36 mL	20.71 mL
5 mM	0.41 mL	2.07 mL	4.14 mL

*The above data is based on the productmolecular weight 482.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Seletalisib (UCB-5857)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions