Tenalisib (RP6530)

Catalog No. A16799

Tenalisib (RP6530)是一种有效且选择性的双重PI3Kδ/PI3Kγ抑制剂，能抑制B细胞淋巴瘤细胞系的生长，同时降低下游生物标记物pAKT。

Technical details

Catalog Num	A16799
M. Wt	415.43
Formula	C23H18FN5O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1639417-53-0
Synonyms	RP-6530, RP 6530
SMILES	O=C1C(C2=CC=CC(F)=C2)=C([C@@H](NC3=C4NC=NC4=NC=N3)CC)OC5=C1C=CC=C5

Biological Activity

Tenalisib (RP6530)是一种有效且选择性的双重PI3Kδ/PI3Kγ抑制剂，能抑制B细胞淋巴瘤细胞系的生长，同时降低下游生物标记物pAKT。

Solubility *

In vitro	DMSO	74 mg/mL (178.13 mM)
	Water	Insoluble
	Ethanol	74 mg/mL (178.13 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.07 mL	120.36 mL	240.71 mL
0.5 mM	4.81 mL	24.07 mL	48.14 mL
1 mM	2.41 mL	12.04 mL	24.07 mL
5 mM	0.48 mL	2.41 mL	4.81 mL

*The above data is based on the productmolecular weight 415.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Tenalisib (RP6530)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions