GDC-0575 (ARRY-575, RG7741)

Catalog No. A16811

GDC-0575 (ARRY-575,RG7741)是一种有效的选择性CHK1抑制剂，IC50为1.2 nM。

Technical details

Catalog Num	A16811
M. Wt	378.27
Formula	C16H20BrN5O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1196541-47-5
Synonyms	GDC-0575; GDC 0575; GDC0575; ARRY-575; ARRY-575; ARRY575; RG7741; RG-7741; RG 7741; AK 687476; AK-687476; AK687476;
SMILES	O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32

Biological Activity

GDC-0575 (ARRY-575,RG7741)是一种有效的选择性CHK1抑制剂，IC50为1.2 nM。

Solubility *

In vitro	DMSO	68 mg/mL (179.76 mM)
	Water	Insoluble
	Ethanol	5 mg/mL (13.21 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.44 mL	132.18 mL	264.36 mL
0.5 mM	5.29 mL	26.44 mL	52.87 mL
1 mM	2.64 mL	13.22 mL	26.44 mL
5 mM	0.53 mL	2.64 mL	5.29 mL

*The above data is based on the productmolecular weight 378.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

GDC-0575 (ARRY-575, RG7741)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions