CBL-0137

Catalog No. A16836

CBL0137 (CBL-0137)在基于细胞的p53和NF-kB报告基因检测中分别激活p53和抑制NF-kB，EC50为0.37 uM和0.47 uM。它还抑制组蛋白伴侣FACT（促进染色质转录复合物）。

Technical details

Catalog Num	A16836
M. Wt	372.89
Formula	C21H24N2O2.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1197397-89-9
Synonyms	CBL0137, CBL 0137, Curaxin 137, Curaxin137, Curaxin-137, CBLC137, CBLC 137, CBLC-137
SMILES	CC(/N=C/CN1C2=C(C3=C1C=CC(C(C)=O)=C3)C=C(C(C)=O)C=C2)C.[H]Cl

Biological Activity

CBL0137 (CBL-0137)在基于细胞的p53和NF-kB报告基因检测中分别激活p53和抑制NF-kB，EC50为0.37 uM和0.47 uM。它还抑制组蛋白伴侣FACT（促进染色质转录复合物）。

Solubility *

In vitro	DMSO	35 mg/mL (93.86 mM)
	Water	22 mg/mL (59 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.82 mL	134.09 mL	268.18 mL
0.5 mM	5.36 mL	26.82 mL	53.64 mL
1 mM	2.68 mL	13.41 mL	26.82 mL
5 mM	0.54 mL	2.68 mL	5.36 mL

*The above data is based on the productmolecular weight 372.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

CBL-0137

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions