PF-06855800

Catalog No. A16860

PF-06855800 (PF06855800)是一种有效的,选择性的,SAM竞争性,BBB渗透性,口服活性的蛋白精氨酸甲基转移酶PRMT5抑制剂,Ki为0.02 nM。
Catalog Num A16860
M. Wt 392.811
Formula C17H16ClFN4O4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1989620-04-3
Synonyms PF06855800, PF 06855800
SMILES NC1=C2C(N([C@H]3[C@@H]([C@@H]([C@@H]([C@@H](C4=CC=C(Cl)C(F)=C4)O)O3)O)O)C=C2)=NC=N1
PF-06855800 (PF06855800)是一种有效的,选择性的,SAM竞争性,BBB渗透性,口服活性的蛋白精氨酸甲基转移酶PRMT5抑制剂,Ki为0.02 nM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.46 mL 127.29 mL 254.58 mL
0.5 mM 5.09 mL 25.46 mL 50.92 mL
1 mM 2.55 mL 12.73 mL 25.46 mL
5 mM 0.51 mL 2.55 mL 5.09 mL

*The above data is based on the productmolecular weight 392.811. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.