JNJ-10229570
Catalog No. A16876
JNJ-10229570是一种新型MC1R和MC5R拮抗剂，用于治疗原代人皮脂细胞。其抑制125I-NDP-α-MSH和人类细胞中MC1R和MC5R结合的IC50值分别为 270 nM 和 200 nM。
| Catalog Num | A16876 |
|---|---|
| M. Wt | 389.47 |
| Formula | C22H19N3O2S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 524923-88-4 |
| Synonyms | JNJ10229570, JNJ 10229570, UNII-N9IX402L35 |
| SMILES | COC1=CC=CC=C1C2=N/C(SN2C3=CC=CC=C3OC)=N\C4=CC=CC=C4 |
JNJ-10229570是一种新型MC1R和MC5R拮抗剂，用于治疗原代人皮脂细胞。其抑制125I-NDP-α-MSH和人类细胞中MC1R和MC5R结合的IC50值分别为 270 nM 和 200 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.68 mL | 128.38 mL | 256.76 mL |
| 0.5 mM | 5.14 mL | 25.68 mL | 51.35 mL |
| 1 mM | 2.57 mL | 12.84 mL | 25.68 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
*The above data is based on the productmolecular weight 389.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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