AZD5991

Catalog No. A16880

AZD-5991是一种有效的选择性Mcl-1抑制剂,在FRET分析中的IC50为0.7 nM,在表面等离子体共振(SPR)分析中的Kd为0.17 nM。
Catalog Num A16880
M. Wt 672.25
Formula C35H34ClN5O3S2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2143061-81-6
Synonyms AZD-5991, AZD 5991
SMILES O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5
AZD-5991是一种有效的选择性Mcl-1抑制剂,在FRET分析中的IC50为0.7 nM,在表面等离子体共振(SPR)分析中的Kd为0.17 nM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.88 mL 74.38 mL 148.75 mL
0.5 mM 2.98 mL 14.88 mL 29.75 mL
1 mM 1.49 mL 7.44 mL 14.88 mL
5 mM 0.3 mL 1.49 mL 2.98 mL

*The above data is based on the productmolecular weight 672.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.