Glecaprevir

Catalog No. A16948

Glecaprevir，也称为ABT-493和A-1282576，是一种新型的HCV NS3/4A蛋白酶抑制剂，IC50值在3.5至11.3 nM之间。

Technical details

Catalog Num	A16948
M. Wt	838.87
Formula	C38H46F4N6O9S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1365970-03-1
Synonyms	ABT-493, ABT493, ABT 493, A-1282576, A1282576, A 1282576
SMILES	O=C([C@H]1N(C2)C([C@H](C(C)(C)C)NC(O[C@@](CCC3)([H])[C@]3([H])OC/C=C/C(F)(F)C4=NC5=CC=CC=C5N=C4O[C@]2([H])C1)=O)=O)N[C@@]6(C(NS(=O)(C7(C)CC7)=O)=O)[C@H](C(F)F)C6

Biological Activity

Glecaprevir，也称为ABT-493和A-1282576，是一种新型的HCV NS3/4A蛋白酶抑制剂，IC50值在3.5至11.3 nM之间。

Solubility *

In vitro	DMSO	99 mg/mL (118.01 mM)
	Water
	Ethanol
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.92 mL	59.6 mL	119.21 mL
0.5 mM	2.38 mL	11.92 mL	23.84 mL
1 mM	1.19 mL	5.96 mL	11.92 mL
5 mM	0.24 mL	1.19 mL	2.38 mL

*The above data is based on the productmolecular weight 838.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Glecaprevir

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions