MK-3903
Catalog No. A17063
MK-3903是有效的选择性AMPK激活剂（EC50 = 8 nM）。口服给药后，MK-3903在小鼠肝脏中表现出强大的靶标参与性，从而改善了小鼠的脂质代谢和胰岛素敏感性。
| Catalog Num | A17063 |
|---|---|
| M. Wt | 454.91 |
| Formula | C27H19ClN2O3 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1219737-12-8 |
| Synonyms | MK3903, MK 3903 |
| SMILES | O=C(O)C1=CC(OC2=NC3=CC(C4=CC=C(C5=CC=CC=C5)C=C4)=C(Cl)C=C3N2)=CC=C1C |
MK-3903是有效的选择性AMPK激活剂（EC50 = 8 nM）。口服给药后，MK-3903在小鼠肝脏中表现出强大的靶标参与性，从而改善了小鼠的脂质代谢和胰岛素敏感性。
| In vitro | DMSO | 82 mg/mL (180.26 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.98 mL | 109.91 mL | 219.82 mL |
| 0.5 mM | 4.4 mL | 21.98 mL | 43.96 mL |
| 1 mM | 2.2 mL | 10.99 mL | 21.98 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
*The above data is based on the productmolecular weight 454.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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