SEL120-34A

Catalog No. A17086

SEL120-34A是一种有效且选择性的CDK8抑制剂,在AML细胞中具有高水平的STAT1和STAT5反式激活域丝氨酸磷酸化活性。
Catalog Num A17086
M. Wt 414.145
Formula C15H18Br2N4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1609522-33-9
Synonyms SEL 120-34A, SEL-120-34A, SEL12034A, SEL 12034A, SEL-12034A
SMILES CC1=C2C3=C(C(Br)=C1Br)CCCN3C(N4CCNCC4)=N2
SEL120-34A是一种有效且选择性的CDK8抑制剂,在AML细胞中具有高水平的STAT1和STAT5反式激活域丝氨酸磷酸化活性。
In vitro DMSO 9 mg/mL (19.97 mM)
Water 77 mg/mL (170.88 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.15 mL 120.73 mL 241.46 mL
0.5 mM 4.83 mL 24.15 mL 48.29 mL
1 mM 2.41 mL 12.07 mL 24.15 mL
5 mM 0.48 mL 2.41 mL 4.83 mL

*The above data is based on the productmolecular weight 414.145. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.