BAY-876

Catalog No. A17216

BAY-876 is a potent and Selective GLUT1 Inhibitor. BAY-876 showed good metabolic stability in?vitro and high oral bioavailability in?vivo.

Product Citations

Rita Paolini, .et al. Transcriptional regulation of glucose transporters in human oral squamous cell carcinoma cells, J Oral Pathol Med, 2022, Sep;51(8):679-683 PMID: 35920070

Technical details

Catalog Num	A17216
M. Wt	496.4256
Formula	C24H16F4N6O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1799753-84-6
Synonyms	BAY 876, BAY876
SMILES	O=C(C1=NC2=CC(F)=CC=C2C(C(NC3=C(C)N(CC4=CC=C(C=C4)C#N)N=C3C(F)(F)F)=O)=C1)N

Biological Activity

BAY-876 is a potent and Selective GLUT1 Inhibitor. BAY-876 showed good metabolic stability in?vitro and high oral bioavailability in?vivo.

Solubility *

In vitro	DMSO	Warmed: 88 mg/mL (177.26 mM)
	Water	Insoluble
	Ethanol	Warmed: 3 mg/mL (6.04 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.14 mL	100.72 mL	201.44 mL
0.5 mM	4.03 mL	20.14 mL	40.29 mL
1 mM	2.01 mL	10.07 mL	20.14 mL
5 mM	0.4 mL	2.01 mL	4.03 mL

*The above data is based on the productmolecular weight 496.4256. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.