Mivebresib (ABBV-075)

Catalog No. A17226

Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing proteind) with potential antineoplastic activity.

Technical details

Catalog Num	A17226
M. Wt	459.4678
Formula	C22H19F2N3O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1445993-26-9
Synonyms	ABBV-075; ABBV 075; ABBV075;
SMILES	CCS(=O)(NC1=CC=C(OC2=CC=C(F)C=C2F)C(C3=CN(C)C(C4=C3C=CN4)=O)=C1)=O

Biological Activity

Mivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing proteind) with potential antineoplastic activity.

Solubility *

In vitro	DMSO	79 mg/mL (171.93 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.76 mL	108.82 mL	217.64 mL
0.5 mM	4.35 mL	21.76 mL	43.53 mL
1 mM	2.18 mL	10.88 mL	21.76 mL
5 mM	0.44 mL	2.18 mL	4.35 mL

*The above data is based on the productmolecular weight 459.4678. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Mivebresib (ABBV-075)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions