SBI-115

Catalog No. A17235

SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.

Technical details

Catalog Num	A17235
M. Wt	340.778
Formula	C14H13ClN2O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	882366-16-7
Synonyms	SBI 115; SBI115;
SMILES	O=C(C1=NC(S(=O)(CC)=O)=NC=C1Cl)OC2=CC=CC(C)=C2

Biological Activity

SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.

Solubility *

In vitro	DMSO	58 mg/mL (170.2 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.34 mL	146.72 mL	293.45 mL
0.5 mM	5.87 mL	29.34 mL	58.69 mL
1 mM	2.93 mL	14.67 mL	29.34 mL
5 mM	0.59 mL	2.93 mL	5.87 mL

*The above data is based on the productmolecular weight 340.778. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

SBI-115

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions