9-Phenanthrol
Catalog No. A17570
Selective TRPM4 blocker (IC50 = 20 μM in HEK293 cells). Exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). Abolishes arrhythmias induced by hypoxia in a mouse heart model.
| Catalog Num | A17570 |
|---|---|
| M. Wt | 194.23 |
| Formula | C14H10O |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 484-17-3 |
| Synonyms | phenanthren-9-ol |
| SMILES | C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O |
Selective TRPM4 blocker (IC50 = 20 μM in HEK293 cells). Exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). Abolishes arrhythmias induced by hypoxia in a mouse heart model.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 51.49 mL | 257.43 mL | 514.85 mL |
| 0.5 mM | 10.3 mL | 51.49 mL | 102.97 mL |
| 1 mM | 5.15 mL | 25.74 mL | 51.49 mL |
| 5 mM | 1.03 mL | 5.15 mL | 10.3 mL |
*The above data is based on the productmolecular weight 194.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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